利用生物基因组学数据库，对绵羊微管解聚蛋白2基因进行生物信息学分析，从而预测STMN2基因编码产物的理化性质以及功能结构域，并构建STMN2同源基因的系统进化树。结果表明，绵羊STMN2基因含有1个540 bp的开放阅读框，编码179个氨基酸；STMN2蛋白分子质量约为12.5 KD，理论等电点为11.57；STMN2编码产物的二级结构主要以α螺旋和无规则卷曲为主，主要位于细胞质中，作为一种生长因子参与机体的调控。

This study aimed to study the bioinformation of sheep STMN2 gene. The physicochemical characteristics， structures and functions of ovine STMN2 are predicted and analyzed with software tools and database. Meanwhile， the phylogenetic tree of STMN2 and related proteins is constructed， The result shows that the ORF of STMN2 is 540 bp which encoded 179 amino acids. The sheep protein of STMN2 is 12.5 KD in molecular weight， 11.57 in isoelectric point. The secondary structure of STMN2 shows that it mainly constituted of α-helix and coils， and important role in reproductive regulation as a growth factor in nucleus.

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甘肃农业大学盛彤笙科技创新基金(GSAU-STS-1525)